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1 September 2006 Myocardial tissue characterization based on a polarization-sensitive optical coherence tomography system with an ultrashort pulsed laser
Chia-Wei Sun, Yih-Ming Wang, Long-Sheng Lu, Chih-Wei Lu, I-Jen Hsu, Meng-Tsan Tsai, Chih-Chung Yang, Yean-Woei Kiang, Chau-Chung Wu M.D.
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Journal of Biomedical Optics, Vol. 11, Issue 5, 054016 (September 2006). https://doi.org/10.1117/1.2363358
Abstract
A polarization-sensitive optical coherence tomography (PSOCT) system using a femtosecond-laser as the broadband light source is implemented with the axial resolution of 5 µm in free space. Through the design of path-length difference between the two polarization inputs and the modulation of one of the polarization inputs, the PSOCT images of various input and output polarization combinations can be distinguished and simultaneously collected. The PSOCT system is then used for in vitro scanning of the myocardium tissues of normal and infarcted rat hearts. The destruction of the birefringence nature of the fiber muscle in the infarcted heart can be clearly observed.
©(2006) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Chia-Wei Sun, Yih-Ming Wang, Long-Sheng Lu, Chih-Wei Lu, I-Jen Hsu, Meng-Tsan Tsai, Chih-Chung Yang, Yean-Woei Kiang, and Chau-Chung Wu M.D. "Myocardial tissue characterization based on a polarization-sensitive optical coherence tomography system with an ultrashort pulsed laser," Journal of Biomedical Optics 11(5), 054016 (1 September 2006). https://doi.org/10.1117/1.2363358
Published: 1 September 2006
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KEYWORDS
Polarization
Tissues
Heart
Optical coherence tomography
Birefringence
Tissue optics
Signal detection
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