Study of dynamic pressure-induced refractive index change using derivative total reflection method

Jin Wang; Qing Ye; Zhichao Deng; Teng-Qian Sun; Wen-Yuan Zhou; Jian-Chun Mei; Chun-Ping Zhang; Jianguo Tian

doi:10.1117/1.JBO.18.11.117005

8 November 2013 Study of dynamic pressure-induced refractive index change using derivative total reflection method

Jin Wang, Qing Ye, Zhichao Deng, Teng-Qian Sun, Wen-Yuan Zhou, Jian-Chun Mei, Chun-Ping Zhang, Jianguo Tian

Author Affiliations +

Funded by: National Basic Research Program of China, Chinese National Key Basic Research Special Fund, Chinese National Key Basic Research Special, Science and Technology Program of Tianjin

Journal of Biomedical Optics, Vol. 18, Issue 11, 117005 (November 2013). https://doi.org/10.1117/1.JBO.18.11.117005

Abstract

We report the dynamic refractive index (RI) change of tissue under a stepped compression load using a custom-built pressure apparatus. Angle-dependent reflectance profiles of biotissue samples are recorded, and the RI values are resolved using the derivative total reflection method. These results are relevant for understanding the mechanism of mechanical optical clearing, for investigating tissue dynamics under mechanical stimuli, and for other biomedical applications.

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Jin Wang, Qing Ye, Zhichao Deng, Teng-Qian Sun, Wen-Yuan Zhou, Jian-Chun Mei, Chun-Ping Zhang, and Jianguo Tian "Study of dynamic pressure-induced refractive index change using derivative total reflection method," Journal of Biomedical Optics 18(11), 117005 (8 November 2013). https://doi.org/10.1117/1.JBO.18.11.117005

Published: 8 November 2013

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