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27 April 2018 Real-time biodetection using a smartphone-based dual-color surface plasmon resonance sensor
Qiang Liu, Huizhen Yuan, Yun Liu, Jiabin Wang, Zhenguo Jing, Wei Peng
Author Affiliations +
Funded by: National Natural Science Foundation of China (NSFC), Natural Science Foundation of China, National Nature Science Foundation of China, National Science Foundation for Postdoctoral Scientists of China
Journal of Biomedical Optics, Vol. 23, Issue 4, 047003 (April 2018). https://doi.org/10.1117/1.JBO.23.4.047003
Abstract
We proposed a compact and cost-effective red–green dual-color fiber optic surface plasmon resonance (SPR) sensor based on the smartphone. Inherent color selectivity of phone cameras was utilized for real-time monitoring of red and green color channels simultaneously, which can reduce the chance of false detection and improve the sensitivity. Because there are no external prisms, complex optical lenses, or diffraction grating, simple optical configuration is realized. It has a linear response in a refractive index range of 1.326 to 1.351 (R2  =  0.991) with a resolution of 2.3  ×  10  −  4  RIU. We apply it for immunoglobulin G (IgG) concentration measurement. Experimental results demonstrate that a linear SPR response was achieved for IgG concentrations varying from 0.02 to 0.30  mg  /  ml with good repeatability. It may find promising applications in the fields of public health and environment monitoring owing to its simple optics design and applicability in real-time, label-free biodetection.
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2018/$25.00 © 2018 SPIE
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Qiang Liu, Huizhen Yuan, Yun Liu, Jiabin Wang, Zhenguo Jing, and Wei Peng "Real-time biodetection using a smartphone-based dual-color surface plasmon resonance sensor," Journal of Biomedical Optics 23(4), 047003 (27 April 2018). https://doi.org/10.1117/1.JBO.23.4.047003
Received: 10 December 2017; Accepted: 30 March 2018; Published: 27 April 2018
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KEYWORDS
Sensors
Fiber optics sensors
Fiber optics
Proteins
Surface plasmons
Cameras
Diffraction gratings
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