Based on the refraction characteristic of uniform and transparent liquid, the measurement error of the liquid refractive index using the internal standard method is analyzed, and an improved laser speckle method is proposed. This method designs a double-cell structure composed of two identical rectangular parallelepiped glass cells with one cell containing the liquid to be measured and the other one being empty. This double-cell structure is placed in the built optical system based on laser speckle, and then the refractive indices of sodium chloride solution and sucrose solution with various concentrations are measured by the improved method. Compared with the measurement values of the Abbe refractometer and the internal standard method, the results show that the improved method can significantly reduce the measurement error and improve the measurement accuracy.