Artificial proteins are created that offer a universal and biocompatible approach to control the morphology of metal nanocrystals.
First, we select, from a large library of artificial proteins (alpha-Repins), individuals that show specific binding for Au(111) facets. Gold nanocrystals synthesized with such -Rep are exclusively terminated by Au(111) planes. The protein-coated nanocrystals are then functionalized to perform biomolecule-driven self-assembly and on-surface enzymatic catalysis.
Alternatively, growth templates with a complex and rigid shape could be constructed from two artificial proteins selected to act as the supercoil unit and the staple that spontaneously self-assemble into helical nanotubular templates observed by cryo-electron microscopy.
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