The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer
(TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ~3.0 μm and etched
by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was
coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid
(DNA).
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