In optical imaging, light propagation is affected by the heterogeneities of the refractive index. At shallow depths, these fluctuations induce wave-front distortions that degrade the image resolution and contrast. Beyond a few scattering mean free paths, multiple scattering starts to predominate and gives rise to a random speckle image without any connection with the medium reflectivity. To overcome these detrimental phenomena, we develop a general matrix approach of optical imaging and demonstrate its benefit by means of numerical simulations. By stacking a set of random phase screens, we model forward multiple scattering and its short-range memory effect. A computational multi-conjugate adaptive optics strategy is then proposed to exploit these snake photons ad optimize the focusing process at any point inside the medium.
Heterogeneities of biological tissues can strongly affect light propagation at large depths by distorting the initial wavefront. Inspired by previous works in acoustics, we have developed a matrix approach to Full-Field Optical Coherence Tomography (FF-OCT) to push back the fundamental limit of aberrations and multiple scattering. An analysis of the correlations of the matrix allows to correct for aberrations and forward multiple scattering over multiple isoplanatic areas (contrary to classic adaptive optics). Here, we report on the application of this approach to the imaging of the monkey cornea and the quantitative measurement of the corneal transparency.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.