The Large Area Detector (LAD) is the high-throughput, spectral-timing instrument onboard the eXTP mission, a flagship mission of the Chinese Academy of Sciences and the China National Space Administration, with a large European participation coordinated by Italy and Spain. The eXTP mission is currently performing its phase B study, with a target launch at the end-2027. The eXTP scientific payload includes four instruments (SFA, PFA, LAD and WFM) offering unprecedented simultaneous wide-band X-ray timing and polarimetry sensitivity. The LAD instrument is based on the design originally proposed for the LOFT mission. It envisages a deployed 3.2 m2 effective area in the 2-30 keV energy range, achieved through the technology of the large-area Silicon Drift Detectors - offering a spectral resolution of up to 200 eV FWHM at 6 keV - and of capillary plate collimators - limiting the field of view to about 1 degree. In this paper we will provide an overview of the LAD instrument design, its current status of development and anticipated performance.
Diffuse fluorescence tomography (DFT) is an emerging optical imaging tool for in-vivo observation of organisms and small-animal. Especially, dynamic diffuse fluorescence tomography can provide contrast-enhanced and comprehensive information for tumor diagnosis and staging with the pharmacokinetic image. However, the conventional reconstruction algorithms for DFT always suffers from low spatial resolution. Multi-modality imaging methods have been proposed to integrate DFT with other imaging modalities with in general intricate and costly experimental apparatus. We developed a dual-modality system that combines the ultrasound imaging and DFT which is simple and low-cost with no ionization damage. The results in phantom experiments demonstrate that with the a priori guidance of ultrasound imaging, the quantitativeness and spatial resolution of the fluorescence image can be considerably improved.
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