Prostate cancer represents 7% of all new cancer cases worldwide. There remain important challenges in the diagnosis and treatment of prostate cancers, particularly to increase biopsy accuracy and to enable nerve-sparing surgery. Here, we explore the capability of wide-field optical coherence tomography (OCT) and optical coherence elastography (OCE), spanning up to 45x45 mm in the lateral field of view and to depths of 1 mm, to accurately identify prostate microarchitecture. In this study, we present novel methodology to systematically validate OCT and OCE images through co-registration with standard histology on 15 human prostate specimens and demonstrate the potential for intraoperative use.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.