We report an in situ formed tunable liquid microlense array and its applications for enhancing dynamic lab-on-a-chip performance. The de-ionized water microlenses are intrinsically formed via liquid-air interfaces of liquid droplets at T-shaped junctions of octadecyltrichlorosilane(OTS) treated polymerized isobornyl acrylate(poly(IBA)) microchannels., and can be separately tuned in focal lengths by pneumatic manipulation. Via the tunable microlenses, excitation light is dynamically focused onto the fluorescent fluidic sample, thus the fluorescence emission signal for detection is amplified. We have further shown the potential for surface reaction study at microfluidic interfaces by the microlense array.
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