Dr. Howard E. Savage Profile

Dr. Howard E. Savage

Cell Biologist at New York Eye and Ear Infirmary

SPIE Involvement:

Author

Publications (30)

Proceedings Article | 12 February 2010 Paper

Changes of collagen, elastin, and tryptophan contents in laser welded porcine aorta tissues studied using fluorescence spectroscopy

C.-H. Liu, W. Wang, V. Kartazaev, H. Savage, R. Alfano

Proceedings Volume 7561, 756115 (2010) https://doi.org/10.1117/12.842429

KEYWORDS: Tissues, Laser welding, Collagen, Luminescence, Proteins, Fluorescence spectroscopy, Laser therapeutics, Absorption, Tissue optics, Surgery

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Proceedings Article | 11 March 2008 Paper

NIR-laser tissue welding in an in vivo guinea pig animal model

Vidyasagar Sriramoju, Howard Savage, A. Katz, Rahul Chakraverty, Yuri Budansky, Rakhi Podder, Naghmeh Davatgarzadeh, Uladzimir Kartazayev, Richard Rosen, R. Alfano

Proceedings Volume 6854, 685405 (2008) https://doi.org/10.1117/12.760044

KEYWORDS: Laser tissue interaction, Laser welding, Tissues, In vivo imaging, Skin, Animal model studies, Near infrared, Laser energy, Collagen, Absorption

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Proceedings Article | 3 March 2008 Paper

Raman spectroscopic study of acute oxidative stress induced changes in mice skeletal muscles

Vidyasagar Sriramoju, Alexandra Alimova, Rahul Chakraverty, A. Katz, S. Gayen, L. Larsson, H. Savage, R. Alfano

Proceedings Volume 6853, 685315 (2008) https://doi.org/10.1117/12.761277

KEYWORDS: Raman spectroscopy, Tissues, Luminescence, Oxygen, Fluorescence spectroscopy, Spectroscopy, Ions, Hydrogen, In vivo imaging, Oxidation

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Proceedings Article | 13 February 2007 Paper

Optical high resolution cross section imaging of a human breast model using independent component analysis

M. Xu, M. Alrubaiee, S. Gayen, H. Savage, R. Alfano

Proceedings Volume 6434, 643416 (2007) https://doi.org/10.1117/12.703574

KEYWORDS: Breast, Scattering, Tissues, Independent component analysis, Tissue optics, Light, Cancer, Image resolution, Absorption, Optical imaging

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Proceedings Article | 22 February 2006 Paper

Heat management prevents tissue buckling and collateral damage in NIR-laser welding

Vidyasagar Sriramoju, Howard Savage, Rabindra Halder, Richard Rosen, A. Katz, R. Alfano

Proceedings Volume 6078, 60780Y (2006) https://doi.org/10.1117/12.649830

KEYWORDS: Laser tissue interaction, Tissues, Laser welding, Near infrared, Fiber lasers, Collagen, Diamond, Erbium, Wound healing, Computing systems

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Proceedings Article | 25 April 2005 Paper

In vitro NIR laser tissue welding of porcine ocular tissues

Richard Rosen, Howard Savage, Rabindra Halder, Uladzimir Kartazayeu, Steven McCormick, Alvin Katz, Henry Perry, Robert Alfano

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.591361

KEYWORDS: Tissues, Cornea, Laser tissue interaction, Near infrared, Laser welding, Laser systems engineering, Fiber lasers, Erbium, Microscopy, Sclera

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Proceedings Article | 25 April 2005 Paper

Optimization of near-infrared laser tissue welding of porcine cornea: a Monte Carlo-aided dosimetry study

Neil Patel, Howard Savage, Richard Rosen, Rabindra Halder, Uladzimir Kartazayeu, Steven McCormick, Alvin Katz, Henry Perry, Robert Alfano

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.589804

KEYWORDS: Laser tissue interaction, Cornea, Laser welding, Monte Carlo methods, Absorption, Tissues, Photons, Laser systems engineering, Laser scattering, Scattering

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Proceedings Article | 25 April 2005 Paper

Laser skin welding using water absorption and heat management

Rabindra Halder, Alvin Katz, Howard Savage, Vladimir Kartazayev, Steven McCormick, Yury Budansky, Misu Paul, Richard Rosen, Robert Alfano

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.592795

KEYWORDS: Skin, Laser welding, Tissues, Collagen, Absorption, Birefringence, Glasses, Laser tissue interaction, Photomicroscopy, Wound healing

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Proceedings Article | 13 July 2004 Paper

NIR laser tissue welding of in vitro porcine of cornea and sclera tissue

Richard Rosen, Howard Savage, Ramindra Halder, Uladzimir Kartazayeu, Tapan Gayen, Steven McCormick, Alvin Katz, Henry Perry, Robert Alfano

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.531019

KEYWORDS: Tissues, Laser tissue interaction, Cornea, Sclera, Laser welding, Near infrared, Eye, In vitro testing, Laser systems engineering, Control systems

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Proceedings Article | 8 March 2004 Paper

Time-resolved and steady-state fluorescence spectroscopy from bacteria subjected to bactericidal agents

Alvin Katz, Alexandra Alimova, Masood Siddique, Howard Savage, Mahendra Shah, Richard Rosen, Robert Alfano

Proceedings Volume 5269, (2004) https://doi.org/10.1117/12.518656

KEYWORDS: Bacteria, Luminescence, Fluorescence spectroscopy, Sodium, Hydrogen, Ultraviolet radiation, Absorbance, Time resolved spectroscopy

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Proceedings Article | 12 September 2003 Paper

Raman and fluorescence spectroscopic evaluation of NIR laser welded human and porcine aorta tissues

Alvin Katz, Alexandra Alimova, Glenn Minko, C. Liu, Tapan Gayen, Howard Savage, Rabindra Halder, Steven McCormick, Robert Alfano

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.476390

KEYWORDS: Raman spectroscopy, Tissues, Luminescence, Collagen, Natural surfaces, Near infrared, Laser welding, Spectroscopy, Fluorescence spectroscopy, Near infrared spectroscopy

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Proceedings Article | 12 September 2003 Paper

Near-infrared laser welding of aortic and skin tissues and microscopic investigation of welding efficacy

Tapan Gayen, Alvin Katz, Howard Savage, John Lee, M. Paul, Rabindra Halder, Steven McCormick, Robert Alfano

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.476392

KEYWORDS: Tissues, Skin, Laser welding, Collagen, Absorption, Scanning electron microscopy, Photomicroscopy, Fiber lasers, Chromium, Erbium

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Proceedings Article | 23 July 2003 Paper

In situ identification of bacteria size by light scattering

Alvin Katz, Alexandra Alimova, Min Xu, Elizabeth Rudolph, Howard Savage, Mahendra Shah, Steven McCormick, Richard Rosen, Robert Alfano

Proceedings Volume 4965, (2003) https://doi.org/10.1117/12.479188

KEYWORDS: Light scattering, Bacteria, Particles, Scattering, Protactinium, Scatter measurement, Optical testing, Optical spheres, Scanning electron microscopy, Microorganisms

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Proceedings Article | 23 July 2003 Paper

In situ changes in native fluorescence from Bacillus subtilis during

Alvin Katz, Alexandra Alimova, Glenn Minko, Howard Savage, Daniel Will, Mahendra Shah, Richard Rosen, Robert Alfano

Proceedings Volume 4965, (2003) https://doi.org/10.1117/12.479189

KEYWORDS: Luminescence, Bacteria, Absorption, Iron, Eye, Ear, Fluorescence spectroscopy, Carbon, Spectroscopy, Calcium

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Proceedings Article | 17 June 2002 Paper

Near-infrared welding of aorta and skin tissues using a Cr4+:YAG laser

Tapan Gayen, Alvin Katz, Yury Budansky, Jonathan Evans, Shixiang Xu, Howard Savage, Steven McCormick, Robert Alfano

Proceedings Volume 4609, (2002) https://doi.org/10.1117/12.432085

KEYWORDS: Tissues, Skin, Laser welding, YAG lasers, Absorption, Luminescence, Laser therapeutics, Collagen, Tunable lasers, Scanning electron microscopy

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Proceedings Article | 1 May 2002 Paper

Noninvasive fluorescence and Raman spectroscopic analysis of laser welded aorta and skin tissue

Alvin Katz, Tapan Gayen, Glenn Minko, Alexandra Alimova, Howard Savage, Steven McCormick, Robert Alfano

Proceedings Volume 4613, (2002) https://doi.org/10.1117/12.465228

KEYWORDS: Luminescence, Collagen, Raman spectroscopy, Skin, Laser tissue interaction, Tissues, Laser welding, Natural surfaces, Laser spectroscopy, Spectroscopy

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Proceedings Article | 19 April 2000 Paper

Ultraviolet 2D fluorescence mapping system for the imaging of head and neck tumors

Alvin Katz, Howard Savage, Fanan Zeng, Jayson Rome, Stimson Schantz, Steven McCormick, Rubina Cocker, Robert Alfano

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382727

KEYWORDS: Luminescence, Tissues, Cancer, Tumors, Collagen, Imaging systems, Ultraviolet radiation, Head, Neck, Pathology

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Proceedings Article | 19 April 2000 Paper

Ultraviolent and blue 2D fluorescence mapping of gynecological tissues

Alvin Katz, Howard Savage, Yuanlong Yang, Fanan Zeng, Jayson Rome, Steven McCormick, Rubina Cocker, Yizhong Yu, Robert Alfano

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382734

KEYWORDS: Tissues, Luminescence, Tumors, Cancer, Collagen, Ultraviolet radiation, Cervical cancer, Pathology, Image analysis, Shape analysis

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Proceedings Article | 15 July 1999 Paper

Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography

Yici Guo, Howard Savage, Feng Liu, Stimson Schantz, Peng Ho, Robert Alfano

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356846

KEYWORDS: Tissues, Second-harmonic generation, Tomography, Harmonic generation, Tissue optics, Optical tomography, Natural surfaces, Scattering, Beam splitters, Signal attenuation

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Proceedings Article | 15 July 1999 Paper

Investigation of Barrett's esophagus by ultraviolet and visible fluorescence emission and excitation spectroscopy

Alvin Katz, Paul Basuk, Howard Savage, Mark Chu, Nasser Altorki, Tom Godwin, Steven McCormick, Robert Alfano

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356835

KEYWORDS: Cancer, Esophagus, Tissues, Tissue optics, Ultraviolet radiation, Luminescence, Biopsy, Fluorescence spectroscopy, Spectroscopy, Endoscopy

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Proceedings Article | 16 April 1998 Paper

Fluorescence ratio mapping system for tissue diagnosis

Alvin Katz, Howard Savage, Fanan Zeng, Jayson Rone, Gui Tang, D. Harris, Jason Koutcher, Stimson Schantz, Robert Alfano

Proceedings Volume 3250, (1998) https://doi.org/10.1117/12.305363

KEYWORDS: Tissues, Luminescence, Tissue optics, Tumors, Imaging systems, Breast, Video, Esophagus, Computing systems, Cameras

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Proceedings Article | 16 April 1998 Paper

Second harmonic and two-photon fluorescence histology of tissues

Yici Guo, Feng Liu, Quan-Zhen Wang, Niclolay Zhadin, Peng Ho, Howard Savage, D. Harris, Peter Sacks, Stimson Schantz, Robert Alfano

Proceedings Volume 3250, (1998) https://doi.org/10.1117/12.305381

KEYWORDS: Tissues, Luminescence, Laser scattering, Scattering, Nonlinear optics, Natural surfaces, Second-harmonic generation, Laser applications, Ultrafast phenomena, Optical imaging

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Proceedings Article | 16 April 1998 Paper

Optical fluorescence and Raman biopsy of squamous cell carcinoma from the head and neck

Yuanlong Yang, C. Liu, Howard Savage, Stimson Schantz, Robert Alfano

Proceedings Volume 3250, (1998) https://doi.org/10.1117/12.305364

KEYWORDS: Tissues, Raman spectroscopy, Neck, Head, Luminescence, Lymphatic system, Tumors, Spectroscopy, Biopsy, Diagnostics

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Proceedings Article | 8 November 1996 Paper

Temporal polarization preservation in human breast tissue: a method for optical imaging

Stavros Demos, Howard Savage, Alexandra Heerdt, Stimson Schantz, Robert Alfano

Proceedings Volume 2965, (1996) https://doi.org/10.1117/12.257381

KEYWORDS: Polarization, Tissues, Tissue optics, Breast, Tumors, Optical imaging, Cancer, Picosecond phenomena, Laser tissue interaction, Light wave propagation

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Proceedings Article | 5 April 1996 Paper

Optical biopsy fiber-based fluorescence spectroscopy instrumentation

Alvin Katz, Singaravelu Ganesan, Yuanlong Yang, Gui Tang, Yury Budansky, Edward Celmer, Howard Savage, Stimson Schantz, Robert Alfano

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237579

KEYWORDS: Tissues, Breast, Luminescence, Fluorescence spectroscopy, Diagnostics, In vivo imaging, Biopsy, Ultraviolet radiation, Tissue optics, Tumors

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Proceedings Article | 5 April 1996 Paper

Influence of keratin on native cellular fluorescence of human skin

Rick Davis, Howard Savage, Peter Sacks, Robert Alfano, Stimson Schantz

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237590

KEYWORDS: Skin, Luminescence, Tissues, In vivo imaging, Spectrophotometry, Collagen, Tumors, Xenon, Signal detection, Proteins

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Proceedings Article | 12 April 1995 Paper

Development of in-vitro models to elucidate mechanisms of intrinsic cellular and tissue fluorescence

Howard Savage, Venkateswara Kolli, Sanjoy Saha, Jian Zhang, Mark Glasgold, Peter Sacks, Robert Alfano, Stimson Schantz

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206835

KEYWORDS: Luminescence, Systems modeling, Tumor growth modeling, Control systems, Tissues, Tumors, Signal attenuation, Collagen, In vitro testing, Cancer

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Proceedings Article | 12 April 1995 Paper

Innate tissue fluorescence of the oral mucosa of controls and head-and-neck cancer patients

Howard Savage, Venkateswara Kolli, John Ansley, Rajiv Chandawarkar, Robert Alfano, Stimson Schantz

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206804

KEYWORDS: Tissues, Luminescence, Tongue, Control systems, Tumors, Cancer, Collagen, Head, Neck, Statistical analysis

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Proceedings Article | 19 May 1994 Paper

Tissue autofluorescence spectroscopy: in-vivo alterations may reflect cellular proliferation

Howard Savage, Venkateswara Kolli, Jian Zhang, Robert Alfano, Peter Sacks, Stimson Schantz

Proceedings Volume 2135, (1994) https://doi.org/10.1117/12.175991

KEYWORDS: Cancer, Tongue, In vivo imaging, Tumors, Tissues, Luminescence, In vitro testing, Spectroscopy, Modulation, Fluorescence spectroscopy

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Proceedings Article | 27 August 1993 Paper

Tissue autofluorescence spectroscopy: an intermediate endpoint for chemopreventive agents

Stimson Schantz, Howard Savage, Peter Sacks, Michael Silverberg, Martin Lipkin, Kan Yang, Gui Tang, Robert Alfano

Proceedings Volume 1887, (1993) https://doi.org/10.1117/12.151181

KEYWORDS: Luminescence, Cancer, Tissue optics, Tissues, Spectroscopy, Fluorescence spectroscopy, Molecular spectroscopy, In vivo imaging, Monoclonal antibodies, Tumors

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Showing 5 of 30 publications

Conference Committee Involvement (1)

Optical Biopsy V

27 January 2004 | San Jose, CA, United States

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