Prof. Andreas H. Hielscher Profile

Prof. Andreas H. Hielscher

Professor and Chair at New York Univ

SPIE Involvement:

Author

Publications (124)

SPIE Journal Paper | 24 December 2024 Open Access

Evaluating hemodynamic response to treatment in patients with peripheral arterial disease using dynamic vascular optical spectroscopy

Nisha Maheshwari, Alessandro Marone, Stephen H. K. Kim, Danielle Bajakian, Andreas Hielscher

JBO, Vol. 29, Issue 12, 127001, (December 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.12.127001

KEYWORDS: Hemodynamics, Blood, Vascular diseases, Selenium, Arteries, Statistical analysis, Optical spectroscopy, Angiography, Optical sensing, Data modeling

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Proceedings Article | 27 March 2024 Poster + Paper

Design of a flexible dynamic optical spectroscopic system for monitoring blood oxygenation status in the carotid artery

Lokesh Sharma, Nisha Maheshwari, Alessandro Marone, Hyun Kim, Albert Favate, Andreas Hielscher

Proceedings Volume 12850, 128500O (2024) https://doi.org/10.1117/12.3003762

KEYWORDS: Arteries, Blood, Optical spectroscopy, Optical sensing, Design, Sensors, Tissue optics, Medical imaging

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Proceedings Article | 27 March 2024 Poster + Paper

Preliminary study to assess vascular health for future use in patients with peripheral arterial disease using pressure dependent dynamic optical spectroscopy

N. Maheshwari, A. Marone, S. H. Kim, A. Hielscher

Proceedings Volume 12850, 128500N (2024) https://doi.org/10.1117/12.3003478

KEYWORDS: Tissues, Vascular diseases, Arteries, Sensors, Optical spectroscopy, Hemodynamics, Surgery, Photodetectors, Data acquisition

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Proceedings Article | 27 March 2024 Poster + Paper

Development of a patient-friendly optical imaging system for simultaneous monitoring arthritis in multiple finger joints of patients with systemic lupus erythematosus

Moegammad Bardien, Alessandro Marone, Xin Wang, Shane Murray, Wei Tang, Sean Inzerillo, Vedant Gaikwad, Leila Khalili, Stephen H. Kim, Anca Askanase, Andreas Hielscher

Proceedings Volume 12850, 128500P (2024) https://doi.org/10.1117/12.3003896

KEYWORDS: Arthritis, Optical imaging, Imaging systems, Optical sensing, Signal to noise ratio, Blood pressure, Data acquisition, Medicine, Light emitting diodes, Sensors

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Proceedings Article | 16 March 2023 Presentation + Paper

Preliminary study monitoring hemodynamics using dynamic vascular optical spectroscopy during a surgical intervention

N. Maheshwari, A. Marone, S. H. Kim, D. R. Bajakian, A. Hielscher

Proceedings Volume 12387, 1238702 (2023) https://doi.org/10.1117/12.2650329

KEYWORDS: Balloons, Contrast agents, Arteries, Optical spectroscopy, Vascular diseases, Surgery, Optical sensing, Angiography, Hemodynamics, Blood

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Proceedings Article | 16 March 2023 Poster + Paper

High-speed fluorescence molecular tomography reconstructions through a sparsity constrained neural network

Fay Wang, Andreas Hielscher, Stephen Hyunkeol Kim

Proceedings Volume 12390, 123900G (2023) https://doi.org/10.1117/12.2649022

KEYWORDS: Fluorescence, Education and training, Absorption, Quantum networks, Neural networks, Reconstruction algorithms, Fluorescence tomography, Tissues, Image restoration, Neuroimaging

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SPIE Journal Paper | 8 March 2023 Open Access

Unrolled-DOT: an interpretable deep network for diffuse optical tomography

Yongyi Zhao, Ankit Raghuram, Fay Wang, Stephen Hyunkeol Kim, Andreas Hielscher, Jacob Robinson, Ashok Veeraraghavan

JBO, Vol. 28, Issue 03, 036002, (March 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.3.036002

KEYWORDS: Image restoration, Education and training, Reconstruction algorithms, Machine learning, Image quality, Data modeling, Diffuse optical tomography, Optical networks, Matrices, Visualization

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SPIE Journal Paper | 24 December 2022 Open Access

Postintervention monitoring of peripheral arterial disease wound healing using dynamic vascular optical spectroscopy

Nisha Maheshwari, Alessandro Marone, Mirella Altoé, Stephen H. Kim, Danielle Bajakian, Andreas Hielscher

JBO, Vol. 27, Issue 12, 125002, (December 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.12.125002

KEYWORDS: Wound healing, Arteries, Data acquisition, Diseases and disorders, Vascular diseases, Lab on a chip, Blood, Optical spectroscopy, Animal model studies, Optical sensing

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Proceedings Article | 4 March 2022 Presentation + Paper

Early treatment window for predicting breast cancer response to neoadjuvant chemotherapy in the HR+/HER2- subgroup using diffuse optical tomography

Mirella Altoe, Alessandro Marone, Hyun Kim, Mariella Tejada, Hanina Hibshoosh, Hua Guo, Katherine Crew, Melissa Accordino, Meghna Trivedi, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 11944, 1194403 (2022) https://doi.org/10.1117/12.2609729

KEYWORDS: Breast cancer, Tumors, Breast, Tissue optics, Diffuse optical tomography, Receptors, 3D image processing, Statistical analysis, Surgery, Sensors

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Proceedings Article | 2 March 2022 Poster + Paper

Employing a neural network approach for reducing the convergence speed of diffuse optical image reconstruction algorithms

Fay Wang, Andreas Hielscher, Stephen Kim

Proceedings Volume 11971, 1197109 (2022) https://doi.org/10.1117/12.2609631

KEYWORDS: Neural networks, Data modeling, Image restoration, Absorption, Transform theory, Inverse problems, Temporal resolution, Reconstruction algorithms, Evolutionary algorithms, Tissue optics

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Proceedings Article | 2 March 2022 Poster + Paper

Ultrahigh spatiotemporal resolution fluorescence molecular tomography with a sparsity constrained dimensional reduction reconstruction model

Hyun Kim, Ankit Raghuram, Yongyi Zhao, Ashok Veeraraghavan, Jacob Robinson, Andreas Hielscher

Proceedings Volume 11971, 119710A (2022) https://doi.org/10.1117/12.2610266

KEYWORDS: Data modeling, Absorption, Tomography, Luminescence, Tissues, Spatial resolution, 3D modeling, Fluorescence tomography, Tissue optics, Radiative transfer

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Proceedings Article | 2 March 2022 Presentation + Paper

Initial evaluation of the use of dynamic vascular optical imaging for predicting outcome of surgical intervention to improve blood perfusion in feet of diabetic patients

A. Marone, N. Maheshwari, H. Kim, D. Bajakian, A. Hielscher

Proceedings Volume 11968, 1196809 (2022) https://doi.org/10.1117/12.2610305

KEYWORDS: Blood, Optical imaging, Arteries, Semiconductor lasers, Surgery, Photodetectors, Data acquisition, Blood circulation, Diabetic foot ulcers

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Proceedings Article | 2 March 2022 Presentation + Paper

Pilot study on monitoring ulcer healing with diffuse optical imaging in a patient cohort affected by peripheral arterial disease (PAD)

N. Maheshwari, A. Marone, M. Altoé, H. Kim, D. Bajakian, A. Hielscher

Proceedings Volume 11968, 119680A (2022) https://doi.org/10.1117/12.2610373

KEYWORDS: Data acquisition, Arteries, Diffuse optical imaging, Blood, Visualization, Surgery, Semiconductor lasers, Photodetectors, Blood circulation

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Proceedings Article | 5 March 2021 Presentation + Paper

Total hemoglobin changes in the breast tumors volume of patients undergoing neoadjuvant chemotherapy: a longitudinal analysis

Mirella L. Altoé, Alessandro Marone, Hyun Kim, Hua Guo, Hanina Hibshoosh, Mariella Tejada, Katherine Crew, Melissa Accordino, Meghna Trivedi, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 11639, 1163909 (2021) https://doi.org/10.1117/12.2583101

KEYWORDS: Breast, Tumors, Tissue optics, Surgery, Imaging systems, Tomography, Tissues, Optical testing, Optical imaging, Diffuse optical imaging

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Proceedings Article | 5 March 2021 Presentation + Paper

Vascular optical spectroscopy for the detection of contrast-agent perfusion during x-ray angiography in peripheral artery disease patients undergoing a surgical intervention

A. Marone, M. Smith, N. Maheshwari, H. Kim, D. Bajakian, A. Hielscher

Proceedings Volume 11639, 116390G (2021) https://doi.org/10.1117/12.2582804

KEYWORDS: Angiography, X-rays, Optical spectroscopy, Blood, Arteries, Signal detection, Optical testing

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Proceedings Article | 1 March 2019 Paper

Monitoring total hemoglobin concentration changes across neoadjuvant chemotherapy in PgR-positive and PgR-negative breast cancer with diffuse optical tomography

Mirella Altoe, Alessandro Marone, Hyun Kim, Mariella Tejada, Hanina Hibshoosh, Katherine Crew, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 10874, 108741L (2019) https://doi.org/10.1117/12.2510172

KEYWORDS: Tumors, Breast cancer, Breast, Diffuse optical tomography, Imaging systems, Cancer, Tomography, Breast imaging, Tissue optics, Receptors

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Proceedings Article | 1 March 2019 Paper

New method to diagnose joints affected by systemic lupus erythematosus based on frequency-domain optical transmission

A. Marone, Y. Kim, G. Danias, K. Neville, A. Frantz, T. Kapoor, L. Geraldino-Pardilla, A. Askanase, A. Hielscher

Proceedings Volume 10874, 108740F (2019) https://doi.org/10.1117/12.2509162

KEYWORDS: Diagnostics, Transmittance, Statistical analysis, Rheumatology, Optical tomography, Medicine, Diagnostic tests

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Proceedings Article | 1 March 2019 Paper

Using dynamic vascular optical spectroscopy to evaluate peripheral arterial disease (PAD) in patients who undergo a vascular intervention

A. Marone, J. Hoi, C. Fong, Y. Kim, H. Kim, D. Bajakian, A. Hielscher

Proceedings Volume 10874, 108740E (2019) https://doi.org/10.1117/12.2509116

KEYWORDS: Arteries, Optical spectroscopy, Blood circulation, Surgery, Blood, Data modeling, Data acquisition, Sensors, Reconstruction algorithms, Statistical analysis

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Proceedings Article | 1 March 2019 Paper

Spatial-temporal constraints guided dynamic fluorescence tomographic model for enhanced imaging of organs and functional structures in small animals

Hyun Kim, Jong H. Lee, Dongkyu Kim, Andreas Hielscher, Alessandro Marone

Proceedings Volume 10874, 1087425 (2019) https://doi.org/10.1117/12.2508582

KEYWORDS: Luminescence, Principal component analysis, Tomography, Tumors, Data modeling, Animal model studies, Absorption, 3D modeling, Tissues, Bioluminescence

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Proceedings Article | 20 February 2019 Paper

Flexible electronic bands for the dynamic optical spectroscopic assessment of systemic lupus erythematosus in finger joints

Youngwan Kim, Alessandro Marone, George Danias, Kayla Neville, Andrea Frantz, Teja Kapoor, Laura Geraldino-Pardilla, Hyun K. Kim, Anca Askanase, Ioannis Kymissis, Andreas Hielscher

Proceedings Volume 10885, 108850Z (2019) https://doi.org/10.1117/12.2510305

KEYWORDS: Optical imaging, Hemodynamics, Light emitting diodes, Arthritis, Flexible circuits, Optical spectroscopy, Light sources, Photodetectors

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SPIE Journal Paper | 21 December 2018 Open Access

Special Section Guest Editorial: Pioneer in Biomedical Optics: Introduction to the Special Section in Honor of Steven L. Jacques

Andreas Hielscher, Jessica Ramella-Roman, Lihong Wang

JBO, Vol. 23, Issue 12, 121601, (December 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.12.121601

KEYWORDS: Biomedical optics, Tissue optics, Tissues, Monte Carlo methods, Biomedical engineering, Skin, Biology, Optical properties, Laser tissue interaction, Cancer

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Proceedings Article | 17 February 2017 Paper

Baseline oxygen saturation comparison between pathologic complete responders and extensive residual cancer cases in response to neoadjuvant chemotherapy

Mirella Altoe, Jacqueline Gunther, Emerson Lim, Hyun Keol Kim, Jessica Campbell, Hanina Hibshoosh, Katherine Crew, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 10059, 100590Q (2017) https://doi.org/10.1117/12.2251452

KEYWORDS: Diffuse optical tomography, Breast cancer, Breast imaging, Hemodynamics, Breast, Optical tomography, Tissues, Tumors, Oxygen, Cancer, Imaging systems, Statistical analysis, Error analysis

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Proceedings Article | 16 July 2015 Paper

Combined dynamic and static optical tomography for prediction of treatment outcome in breast cancer patients

Jacqueline Gunther, Emerson Lim, Hyun Keol Kim, Molly Flexman, Lukas Zweck, Sindhiya Arora, Susan Refice, Mindy Brown, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 9538, 953811 (2015) https://doi.org/10.1117/12.2183996

KEYWORDS: Tumors, Chromium, Breast, Hemodynamics, Breast cancer, Chromophores, Imaging systems, Optical tomography, Image restoration, Diffuse optical tomography

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Proceedings Article | 16 July 2015 Paper

Modeling of the blood flow in the lower extremities for dynamic diffuse optical tomography of peripheral artery disease

A. Marone, J. Hoi, M. Khalil, H.K. Kim, G. Shrikhande, R. Dayal, A. Hielscher

Proceedings Volume 9538, 95380Z (2015) https://doi.org/10.1117/12.2183948

KEYWORDS: Arteries, Blood circulation, Blood, Veins, Data modeling, Mathematical modeling, Diffuse optical tomography, Capacitors, Resistance, Resistors

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Proceedings Article | 12 March 2015 Paper

Dynamic diffuse optical tomography for assessing changes of breast tumors during neoadjuvant chemotherapy

Jacqueline Gunther, Emerson Lim, Hyun Keol Kim, Mindy Brown, Susan Refice, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 9319, 93190C (2015) https://doi.org/10.1117/12.2079435

KEYWORDS: Tumors, Breast, Hemodynamics, Diffuse optical tomography, Imaging systems, Breast cancer, Interfaces, Dynamical systems, Sensors, 3D image reconstruction

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Proceedings Article | 5 March 2015 Paper

Characterizing infantile hemangiomas with a near-infrared spectroscopic handheld wireless device

Christopher Fong, Jennifer Hoi, Hyun Kim, Gerald Behr, Lauren Geller, Nina Antonov, Molly Flexman, Maria Garzon, Andreas Hielscher

Proceedings Volume 9319, 931920 (2015) https://doi.org/10.1117/12.2079710

KEYWORDS: Skin, Tissues, Scattering, Oxygen, Tissue optics, Near infrared spectroscopy, Absorption, Spectroscopes, Natural surfaces, Optical properties

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Proceedings Article | 5 March 2015 Paper

A reduced-space basis function neural network method for diffuse optical tomography

Hyun Keol Kim, Jacqueline Gunther, Jennifer Hoi, Andreas Hielscher

Proceedings Volume 9319, 931925 (2015) https://doi.org/10.1117/12.2080550

KEYWORDS: Neural networks, Chromophores, Inverse problems, Tumors, Tissues, Breast, Tissue optics, Imaging systems, Image restoration, Diffuse optical tomography

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Proceedings Article | 4 March 2015 Paper

Non-contact continuous-wave diffuse optical tomographic system to capture vascular dynamics in the foot

Jennifer Hoi, Hyun Kim, Michael Khalil, Christopher Fong, Alessandro Marone, Gautam Shrikhande, Andreas Hielscher

Proceedings Volume 9313, 931312 (2015) https://doi.org/10.1117/12.2080184

KEYWORDS: Blood, Tomography, Arteries, Optical fibers, Continuous wave operation, Diagnostics, Optical imaging, Cameras, Neodymium, Imaging systems

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SPIE Journal Paper | 18 September 2013 Open Access

Optical biomarkers for breast cancer derived from dynamic diffuse optical tomography

Molly Flexman, Hyun Kim, Jacqueline Gunther, Emerson Lim, Maria Alvarez, Elise Desperito, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

JBO, Vol. 18, Issue 09, 096012, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.9.096012

KEYWORDS: Breast, Tumors, Breast cancer, Hemodynamics, Diffuse optical tomography, Tissues, Biomedical optics, 3D image processing, Visualization, Tissue optics

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SPIE Journal Paper | 15 July 2013 Open Access

Computer-aided diagnosis of rheumatoid arthritis with optical tomography, Part 1: feature extraction

Ludguier Montejo, Jingfei Jia, Hyun Kim, Uwe Netz, Sabine Blaschke, Gerhard Mueller, Andreas Hielscher

JBO, Vol. 18, Issue 07, 076001, (July 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.7.076001

KEYWORDS: Computer aided diagnosis and therapy, Feature extraction, Magnetic resonance imaging, Selenium, Optical tomography, Data modeling, Ultrasonography, Virtual colonoscopy, Scattering, Absorption

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SPIE Journal Paper | 15 July 2013 Open Access

Computer-aided diagnosis of rheumatoid arthritis with optical tomography, Part 2: image classification

Ludguier Montejo, Jingfei Jia, Hyun Kim, Uwe Netz, Sabine Blaschke, Gerhard Mueller, Andreas Hielscher

JBO, Vol. 18, Issue 07, 076002, (July 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.7.076002

KEYWORDS: Selenium, Scattering, Computer aided diagnosis and therapy, Image classification, Optical tomography, Data analysis, Neurons, Optimization (mathematics), Absorption, Magnetic resonance imaging

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Proceedings Article | 14 June 2013 Paper

Predicting tumor response in breast cancer patients using diffuse optical tomography

Jacqueline Gunther, Emerson Lim, Hyun Keol Kim, Molly Flexman, Susan Refice, Mindy Brown, Kevin Kalinsky, Dawn Hershman, Andreas Hielscher

Proceedings Volume 8799, 87990P (2013) https://doi.org/10.1117/12.2033352

KEYWORDS: Tumors, Breast cancer, Diffuse optical tomography, Imaging systems, Breast, Sensors, Surgery, Magnetic resonance imaging, Optical fibers, Diffuse optical imaging

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